5JMR
X-ray structure of the furin inhibitory antibody Nb14
Summary for 5JMR
Entry DOI | 10.2210/pdb5jmr/pdb |
Descriptor | camelid VHH fragment, CHLORIDE ION (3 entities in total) |
Functional Keywords | camelid, antibody, inhibitor, furin, immune system |
Biological source | Camelus dromedarius (dromedary) |
Total number of polymer chains | 2 |
Total formula weight | 27363.22 |
Authors | Dahms, S.O.,Than, M.E. (deposition date: 2016-04-29, release date: 2016-12-07, Last modification date: 2024-01-10) |
Primary citation | Dahms, S.O.,Creemers, J.W.,Schaub, Y.,Bourenkov, G.P.,Zogg, T.,Brandstetter, H.,Than, M.E. The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers. Sci Rep, 6:34303-34303, 2016 Cited by PubMed: 27670069DOI: 10.1038/srep34303 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.27 Å) |
Structure validation
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