5JMR

X-ray structure of the furin inhibitory antibody Nb14

Summary for 5JMR

• Entry DOI: 10.2210/pdb5jmr/pdb
• Descriptor: camelid VHH fragment, CHLORIDE ION (3 entities in total)
• Functional Keywords: camelid, antibody, inhibitor, furin, immune system
• Biological source: Camelus dromedarius (dromedary)
• Total number of polymer chains: 2
• Total formula weight: 27363.22

Authors

Dahms, S.O.,Than, M.E. (deposition date: 2016-04-29, release date: 2016-12-07, Last modification date: 2024-01-10)

• Primary citation: Dahms, S.O.,Creemers, J.W.,Schaub, Y.,Bourenkov, G.P.,Zogg, T.,Brandstetter, H.,Than, M.E.; The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers.; Sci Rep, 6:34303-34303, 2016; PubMed: 27670069; DOI: 10.1038/srep34303

Experimental method

X-RAY DIFFRACTION (2.27 Å)