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5JMO

X-ray structure of furin in complex with the inhibitory antibody Nb14

Summary for 5JMO
Entry DOI10.2210/pdb5jmo/pdb
Related PRD IDPRD_000278
DescriptorFurin, camelid VHH fragment, CMK-inhibitor, ... (7 entities in total)
Functional Keywordsprotease, camelid, antibody, complex, hydrolase-antibody complex, furin, hydrolase/antibody
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains6
Total formula weight132677.39
Authors
Dahms, S.O.,Than, M.E. (deposition date: 2016-04-29, release date: 2016-12-07, Last modification date: 2024-01-10)
Primary citationDahms, S.O.,Creemers, J.W.,Schaub, Y.,Bourenkov, G.P.,Zogg, T.,Brandstetter, H.,Than, M.E.
The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers.
Sci Rep, 6:34303-34303, 2016
Cited by
PubMed: 27670069
DOI: 10.1038/srep34303
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.998 Å)
Structure validation

217705

數據於2024-03-27公開中

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