5JMO
X-ray structure of furin in complex with the inhibitory antibody Nb14
Summary for 5JMO
Entry DOI | 10.2210/pdb5jmo/pdb |
Related PRD ID | PRD_000278 |
Descriptor | Furin, camelid VHH fragment, CMK-inhibitor, ... (7 entities in total) |
Functional Keywords | protease, camelid, antibody, complex, hydrolase-antibody complex, furin, hydrolase/antibody |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 132677.39 |
Authors | Dahms, S.O.,Than, M.E. (deposition date: 2016-04-29, release date: 2016-12-07, Last modification date: 2024-01-10) |
Primary citation | Dahms, S.O.,Creemers, J.W.,Schaub, Y.,Bourenkov, G.P.,Zogg, T.,Brandstetter, H.,Than, M.E. The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers. Sci Rep, 6:34303-34303, 2016 Cited by PubMed: 27670069DOI: 10.1038/srep34303 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.998 Å) |
Structure validation
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