5JK7

The X-ray structure of the DDB1-DCAF1-Vpr-UNG2 complex

Summary for 5JK7

• Entry DOI: 10.2210/pdb5jk7/pdb
• Descriptor: DNA damage-binding protein 1, Protein VPRBP, Uracil-DNA glycosylase, ... (4 entities in total)
• Functional Keywords: cullin4-ring e3 ubiquitin ligase hiv-1 vpr ung2, dna binding protein-hydrolase complex, viral protein-dna binding protein complex, viral protein/dna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 410111.08

Authors

Calero, G.,Ahn, J.,Wu, Y. (deposition date: 2016-04-26, release date: 2016-10-05, Last modification date: 2024-03-06)

• Primary citation: Wu, Y.,Zhou, X.,Barnes, C.O.,DeLucia, M.,Cohen, A.E.,Gronenborn, A.M.,Ahn, J.,Calero, G.; The DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction.; Nat.Struct.Mol.Biol., 23:933-940, 2016; PubMed: 27571178; DOI: 10.1038/nsmb.3284

Experimental method

X-RAY DIFFRACTION (3.49 Å)