5JID

Crystal Structure of Human Transthyretin in Complex with Perfluorooctanoic acid (PFOA)

Summary for 5JID

Entry DOI	10.2210/pdb5jid/pdb
Related	1F41 5HJG
Descriptor	Transthyretin, pentadecafluorooctanoic acid, SODIUM ION, ... (4 entities in total)
Functional Keywords	transport protein, thyroxine binding, perfluorooctanoic acid(pfoa)complex
Biological source	Homo sapiens (Human)
Cellular location	Secreted: P02766
Total number of polymer chains	2
Total formula weight	28405.85
Authors	Begum, A.,Zhang, J.,Olofsson, A.,Andersson, P.,Sauer-Eriksson, A.E. (deposition date: 2016-04-22, release date: 2016-10-05, Last modification date: 2024-01-10)
Primary citation	Zhang, J.,Begum, A.,Brannstrom, K.,Grundstrom, C.,Iakovleva, I.,Olofsson, A.,Sauer-Eriksson, A.E.,Andersson, P.L. Structure-Based Virtual Screening Protocol for in Silico Identification of Potential Thyroid Disrupting Chemicals Targeting Transthyretin. Environ. Sci. Technol., 50:11984-11993, 2016 Cited by PubMed: 27668830 DOI: 10.1021/acs.est.6b02771 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation