5JI0

PPARgamma-RXRalpha(S427F) heterodimer in complex with SRC-1, rosiglitazone, and 9-cis-retanoic acid

Summary for 5JI0

• Entry DOI: 10.2210/pdb5ji0/pdb
• Descriptor: Retinoic acid receptor RXR-alpha, Peroxisome proliferator-activated receptor gamma, Nuclear receptor coactivator 1, ... (6 entities in total)
• Functional Keywords: pparg, rxra, src1, agonist, nuclear hormone receptor, heterodimer, bladder cancer, muscle invasive bladder cancer, mibc, transferase
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : P19793 P37231 Q15788
• Total number of polymer chains: 4
• Total formula weight: 64573.85

Authors

Bloudoff, K.,Larsen, N.A. (deposition date: 2016-04-21, release date: 2017-04-26, Last modification date: 2024-11-20)

• Primary citation: Korpal, M.,Zhu, P.,Bloudoff, K.,Larsen, N.A.,Fekkes, P.; PPARgamma-RXRalpha(S427F) heterodimer in complex with SRC-1, rosiglitazone, and 9-cis-retanoic acid; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.98 Å)