5JH5

Structural Basis for the Hierarchical Assembly of the Core of PRC1.1

5JH5 の概要

• エントリーDOI: 10.2210/pdb5jh5/pdb
• 分子名称: Lysine-specific demethylase 2B, S-phase kinase-associated protein 1, Polycomb group RING finger protein 1, ... (5 entities in total)
• 機能のキーワード: gene repression, complex, transcription regulation, transcription repressor, metal binding protein-transcription complex, metal binding protein/transcription
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Nucleus, nucleolus : Q8NHM5; Nucleus : Q9BSM1 Q5H9F3
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 78554.55

構造登録者

Wong, S.J.,Taylor, A.B.,Hart, P.J.,Kim, C.A. (登録日: 2016-04-20, 公開日: 2016-09-14, 最終更新日: 2016-10-19)

• 主引用文献: Wong, S.J.,Gearhart, M.D.,Taylor, A.B.,Nanyes, D.R.,Ha, D.J.,Robinson, A.K.,Artigas, J.A.,Lee, O.J.,Demeler, B.,Hart, P.J.,Bardwell, V.J.,Kim, C.A.; KDM2B Recruitment of the Polycomb Group Complex, PRC1.1, Requires Cooperation between PCGF1 and BCORL1.; Structure, 24:1795-1801, 2016; PubMed: 27568929; DOI: 10.1016/j.str.2016.07.011

実験手法

X-RAY DIFFRACTION (2.55 Å)