5JG6

APC11-Ubv shows role of noncovalent RING-Ubiquitin interactions in processive multiubiquitination and Ubiquitin chain elongation by APC/C

Summary for 5JG6

• Entry DOI: 10.2210/pdb5jg6/pdb
• Descriptor: Anaphase-promoting complex subunit 11, Polyubiquitin-B, ZINC ION, ... (4 entities in total)
• Functional Keywords: ring ubiquitin cell cycle anaphase-promoting complex-cyclosome, cell cycle
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 35004.73

Authors

Brown, N.G.,Zhang, W.,Yu, S.,Miller, D.J.,Sidhu, S.S.,Schulman, B.A. (deposition date: 2016-04-19, release date: 2016-06-15, Last modification date: 2023-09-27)

• Primary citation: Brown, N.G.,VanderLinden, R.,Watson, E.R.,Weissmann, F.,Ordureau, A.,Wu, K.P.,Zhang, W.,Yu, S.,Mercredi, P.Y.,Harrison, J.S.,Davidson, I.F.,Qiao, R.,Lu, Y.,Dube, P.,Brunner, M.R.,Grace, C.R.,Miller, D.J.,Haselbach, D.,Jarvis, M.A.,Yamaguchi, M.,Yanishevski, D.,Petzold, G.,Sidhu, S.S.,Kuhlman, B.,Kirschner, M.W.,Harper, J.W.,Peters, J.M.,Stark, H.,Schulman, B.A.; Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.; Cell, 165:1440-1453, 2016; PubMed: 27259151; DOI: 10.1016/j.cell.2016.05.037

Experimental method

X-RAY DIFFRACTION (2.0013 Å)