5JE1

Crystal structure of Burkholderia glumae ToxA with bound S-adenosylhomocysteine (SAH) and toxoflavin

Summary for 5JE1

• Entry DOI: 10.2210/pdb5je1/pdb
• Related: 5JDY 5JDZ 5JE0 5JE2 5JE3 5JE4 5JE5 5JE6
• Descriptor: Methyl transferase, S-ADENOSYL-L-HOMOCYSTEINE, 1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione, ... (4 entities in total)
• Functional Keywords: n-methyltransferase, s-adenosylmethionine (sam), product complex, toxin, transferase
• Biological source: Burkholderia glumae
• Total number of polymer chains: 2
• Total formula weight: 56793.70

Authors

Fenwick, M.K.,Philmus, B.,Begley, T.P.,Ealick, S.E. (deposition date: 2016-04-17, release date: 2016-05-04, Last modification date: 2024-04-03)

• Primary citation: Fenwick, M.K.,Philmus, B.,Begley, T.P.,Ealick, S.E.; Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis.; Biochemistry, 55:2748-2759, 2016; PubMed: 27070241; DOI: 10.1021/acs.biochem.6b00167

Experimental method

X-RAY DIFFRACTION (1.95 Å)