5JA4
Crystal structure of human TONSL and MCM2 HBDs binding to a histone H3-H4 tetramer
Summary for 5JA4
Entry DOI | 10.2210/pdb5ja4/pdb |
Descriptor | Histone H3.3, Histone H4, DNA replication licensing factor MCM2, ... (7 entities in total) |
Functional Keywords | dna repair and histone chaperone, chaperone |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: P84243 P62805 P49736 Cytoplasm: Q96HA7 |
Total number of polymer chains | 4 |
Total formula weight | 48897.54 |
Authors | |
Primary citation | Saredi, G.,Huang, H.,Hammond, C.M.,Alabert, C.,Bekker-Jensen, S.,Forne, I.,Reveron-Gomez, N.,Foster, B.M.,Mlejnkova, L.,Bartke, T.,Cejka, P.,Mailand, N.,Imhof, A.,Patel, D.J.,Groth, A. H4K20me0 marks post-replicative chromatin and recruits the TONSL-MMS22L DNA repair complex. Nature, 534:714-718, 2016 Cited by PubMed: 27338793DOI: 10.1038/nature18312 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.424 Å) |
Structure validation
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