5J3D

Crystal structure of human Fab 14N4 in complex with post-fusion RSV F

Summary for 5J3D

• Entry DOI: 10.2210/pdb5j3d/pdb
• Related: 5ITB
• Descriptor: 14N4 heavy chain, 14N4 light chain, Fusion glycoprotein F0, ... (4 entities in total)
• Functional Keywords: antibody, virus, complex, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Virion membrane; Single-pass type I membrane protein: P03420 P03420
• Total number of polymer chains: 12
• Total formula weight: 299049.68

Authors

Mousa, J.J.,Crowe, J.E. (deposition date: 2016-03-30, release date: 2016-10-26, Last modification date: 2023-09-27)

• Primary citation: Mousa, J.J.,Sauer, M.F.,Sevy, A.M.,Finn, J.A.,Bates, J.T.,Alvarado, G.,King, H.G.,Loerinc, L.B.,Fong, R.H.,Doranz, B.J.,Correia, B.E.,Kalyuzhniy, O.,Wen, X.,Jardetzky, T.S.,Schief, W.R.,Ohi, M.D.,Meiler, J.,Crowe, J.E.; Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein.; Proc.Natl.Acad.Sci.USA, 113:E6849-E6858, 2016; PubMed: 27791117; DOI: 10.1073/pnas.1609449113

Experimental method

X-RAY DIFFRACTION (4.077 Å)