5IWA

Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with the GE81112 peptide antibiotic

5IWA の概要

• エントリーDOI: 10.2210/pdb5iwa/pdb
• 分子名称: 30S ribosomal protein S2, 30S ribosomal protein S11, 30S ribosomal protein S12, ... (24 entities in total)
• 機能のキーワード: protein synthesis, translation initiation, ribosome, antibiotic, translation
• 由来する生物種: Thermus thermophilus HB8; 詳細
• タンパク質・核酸の鎖数: 21
• 化学式量合計: 769656.87

構造登録者

Schedlbauer, A.,Kaminishi, T.,Ochoa-Lizarralde, B.,Chieko, N.,Masahito, K.,Takemoto, C.,Yokoyama, S.,Connell, S.R.,Fucini, P. (登録日: 2016-03-22, 公開日: 2016-04-27, 最終更新日: 2024-01-10)

• 主引用文献: Fabbretti, A.,Schedlbauer, A.,Brandi, L.,Kaminishi, T.,Giuliodori, A.M.,Garofalo, R.,Ochoa-Lizarralde, B.,Takemoto, C.,Yokoyama, S.,Connell, S.R.,Gualerzi, C.O.,Fucini, P.; Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding.; Proc.Natl.Acad.Sci.USA, 113:E2286-E2295, 2016; PubMed: 27071098; DOI: 10.1073/pnas.1521156113

実験手法

X-RAY DIFFRACTION (3.5 Å)