5IS8

Crystal structure of mouse CARM1 in complex with inhibitor SA0271

5IS8 の概要

• エントリーDOI: 10.2210/pdb5is8/pdb
• 分子名称: Histone-arginine methyltransferase CARM1, 5'-{[(3S)-3-amino-3-carboxypropyl](2-chloroethyl)amino}-5'-deoxyadenosine, 1,2-ETHANEDIOL, ... (5 entities in total)
• 機能のキーワード: protein arginine methyltransferase, catalytic domain, chromatin regulator, mrna processing, mrna splicing, nucleus, s-adenosyl-l-methionine, transcription, transcription regulation, transferase
• 由来する生物種: Mus musculus (Mouse)
• 細胞内の位置: Nucleus: Q9WVG6
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 174299.36

構造登録者

Cura, V.,Marechal, N.,Mailliot, J.,Troffer-Charlier, N.,Hassenboehler, P.,Wurtz, J.M.,Bonnefond, L.,Cavarelli, J. (登録日: 2016-03-15, 公開日: 2017-03-15, 最終更新日: 2024-01-10)

• 主引用文献: Cura, V.,Marechal, N.,Mailliot, J.,Troffer-Charlier, N.,Wurtz, J.M.,Bonnefond, L.,Cavarelli, J.; Crystal structure of mouse CARM1 in complex with inhibitor SA0271; To Be Published,

実験手法

X-RAY DIFFRACTION (2.709 Å)