5IRC
p190A GAP domain complex with RhoA
Summary for 5IRC
Entry DOI | 10.2210/pdb5irc/pdb |
Descriptor | Rho GTPase-activating protein 35, Transforming protein RhoA, CHLORIDE ION, ... (7 entities in total) |
Functional Keywords | protein-protein complex, transition state, gtpase, gap domain, protein binding |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 4 |
Total formula weight | 89458.46 |
Authors | Derewenda, U.,Derewenda, Z. (deposition date: 2016-03-12, release date: 2016-08-17, Last modification date: 2019-12-25) |
Primary citation | Amin, E.,Jaiswal, M.,Derewenda, U.,Reis, K.,Nouri, K.,Koessmeier, K.T.,Aspenstrom, P.,Somlyo, A.V.,Dvorsky, R.,Ahmadian, M.R. Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS. J.Biol.Chem., 291:20353-20371, 2016 Cited by PubMed: 27481945DOI: 10.1074/jbc.M116.736967 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.72 Å) |
Structure validation
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