5IN3

Crystal structure of glucose-1-phosphate bound nucleotidylated human galactose-1-phosphate uridylyltransferase

5IN3 の概要

• エントリーDOI: 10.2210/pdb5in3/pdb
• 分子名称: Galactose-1-phosphate uridylyltransferase, ZINC ION, 5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE, ... (6 entities in total)
• 機能のキーワード: galt, ump-galt, glucose-1-phosphate, galactose-1-phosphate uridylyltransferase, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 94994.99

構造登録者

Kopec, J.,McCorvie, T.,Tallant, C.,Velupillai, S.,Shrestha, L.,Fitzpatrick, F.,Patel, D.,Chalk, R.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.,Edwards, A.,Bountra, C.,Yue, W.W. (登録日: 2016-03-07, 公開日: 2016-03-30, 最終更新日: 2024-01-10)

• 主引用文献: McCorvie, T.J.,Kopec, J.,Pey, A.L.,Fitzpatrick, F.,Patel, D.,Chalk, R.,Shrestha, L.,Yue, W.W.; Molecular basis of classic galactosemia from the structure of human galactose 1-phosphate uridylyltransferase.; Hum.Mol.Genet., 25:2234-2244, 2016; PubMed: 27005423; DOI: 10.1093/hmg/ddw091

実験手法

X-RAY DIFFRACTION (1.73 Å)