5IM4
Crystal structure of designed two-component self-assembling icosahedral cage I52-32
Summary for 5IM4
| Entry DOI | 10.2210/pdb5im4/pdb |
| Descriptor | 6,7-dimethyl-8-ribityllumazine synthase, Phosphotransferase system, mannose/fructose-specific component IIA (2 entities in total) |
| Functional Keywords | icosahedron, designed protein cage, two-component, computational design, protein engineering, rosetta, self-assembling, co-assembling, multimerization, symmetry, nanomaterial, nanostructure, protein binding |
| Biological source | Candida albicans P37005 More |
| Total number of polymer chains | 40 |
| Total formula weight | 665301.76 |
| Authors | Liu, Y.A.,Cascio, D.,Sawaya, M.R.,Bale, J.B.,Collazo, M.J.,Thomas, C.,Sheffler, W.,King, N.P.,Baker, D.,Yeates, T.O. (deposition date: 2016-03-05, release date: 2016-07-27, Last modification date: 2023-09-27) |
| Primary citation | Bale, J.B.,Gonen, S.,Liu, Y.,Sheffler, W.,Ellis, D.,Thomas, C.,Cascio, D.,Yeates, T.O.,Gonen, T.,King, N.P.,Baker, D. Accurate design of megadalton-scale two-component icosahedral protein complexes. Science, 353:389-394, 2016 Cited by PubMed: 27463675DOI: 10.1126/science.aaf8818 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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