5IM4

Crystal structure of designed two-component self-assembling icosahedral cage I52-32

5IM4 の概要

• エントリーDOI: 10.2210/pdb5im4/pdb
• 分子名称: 6,7-dimethyl-8-ribityllumazine synthase, Phosphotransferase system, mannose/fructose-specific component IIA (2 entities in total)
• 機能のキーワード: icosahedron, designed protein cage, two-component, computational design, protein engineering, rosetta, self-assembling, co-assembling, multimerization, symmetry, nanomaterial, nanostructure, protein binding
• 由来する生物種: Candida albicans P37005; 詳細
• タンパク質・核酸の鎖数: 40
• 化学式量合計: 665301.76

構造登録者

Liu, Y.A.,Cascio, D.,Sawaya, M.R.,Bale, J.B.,Collazo, M.J.,Thomas, C.,Sheffler, W.,King, N.P.,Baker, D.,Yeates, T.O. (登録日: 2016-03-05, 公開日: 2016-07-27, 最終更新日: 2023-09-27)

• 主引用文献: Bale, J.B.,Gonen, S.,Liu, Y.,Sheffler, W.,Ellis, D.,Thomas, C.,Cascio, D.,Yeates, T.O.,Gonen, T.,King, N.P.,Baker, D.; Accurate design of megadalton-scale two-component icosahedral protein complexes.; Science, 353:389-394, 2016; PubMed: 27463675; DOI: 10.1126/science.aaf8818

実験手法

X-RAY DIFFRACTION (3.5 Å)