5IIT

Structure of SPX domain of the yeast inorganic polyphophate polymerase Vtc4 crystallized by carrier-driven crystallization in fusion with the macro domain of human histone macroH2A1.1

Summary for 5IIT

Entry DOI	10.2210/pdb5iit/pdb
Descriptor	Vacuolar transporter chaperone 4,Core histone macro-H2A.1, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, ... (6 entities in total)
Functional Keywords	helical bundle, alpha-helical hairpin, inositol phosphate binding protein, protein-protein interaction, chaperone
Biological source	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More
Cellular location	Nucleus : O75367
Total number of polymer chains	4
Total formula weight	170463.89
Authors	Wild, R.,Hothorn, M. (deposition date: 2016-03-01, release date: 2016-04-27, Last modification date: 2024-01-10)
Primary citation	Wild, R.,Gerasimaite, R.,Jung, J.Y.,Truffault, V.,Pavlovic, I.,Schmidt, A.,Saiardi, A.,Jessen, H.J.,Poirier, Y.,Hothorn, M.,Mayer, A. Control of eukaryotic phosphate homeostasis by inositol polyphosphate sensor domains. Science, 352:986-990, 2016 Cited by PubMed: 27080106 DOI: 10.1126/science.aad9858 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.134 Å)

Structure validation