5IIT

Structure of SPX domain of the yeast inorganic polyphophate polymerase Vtc4 crystallized by carrier-driven crystallization in fusion with the macro domain of human histone macroH2A1.1

5IIT の概要

• エントリーDOI: 10.2210/pdb5iit/pdb
• 分子名称: Vacuolar transporter chaperone 4,Core histone macro-H2A.1, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, ... (6 entities in total)
• 機能のキーワード: helical bundle, alpha-helical hairpin, inositol phosphate binding protein, protein-protein interaction, chaperone
• 由来する生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); 詳細
• 細胞内の位置: Nucleus : O75367
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 170463.89

構造登録者

Wild, R.,Hothorn, M. (登録日: 2016-03-01, 公開日: 2016-04-27, 最終更新日: 2024-01-10)

• 主引用文献: Wild, R.,Gerasimaite, R.,Jung, J.Y.,Truffault, V.,Pavlovic, I.,Schmidt, A.,Saiardi, A.,Jessen, H.J.,Poirier, Y.,Hothorn, M.,Mayer, A.; Control of eukaryotic phosphate homeostasis by inositol polyphosphate sensor domains.; Science, 352:986-990, 2016; PubMed: 27080106; DOI: 10.1126/science.aad9858

実験手法

X-RAY DIFFRACTION (2.134 Å)