5IH4
Human Casein Kinase 1 isoform delta apo (kinase domain)
Summary for 5IH4
Entry DOI | 10.2210/pdb5ih4/pdb |
Descriptor | Casein kinase I isoform delta, ZINC ION, S,R MESO-TARTARIC ACID, ... (5 entities in total) |
Functional Keywords | kinase domain, stem cell reprogramming, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: P48730 |
Total number of polymer chains | 1 |
Total formula weight | 34614.15 |
Authors | Ursu, A.,Illich, D.J.,Takemoto, Y.,Porfetye, A.T.,Zhang, M.,Brockmeyer, A.,Janning, P.,Watanabe, N.,Osada, H.,Vetter, I.R.,Ziegler, S.,Schoeler, H.R.,Waldmann, H. (deposition date: 2016-02-29, release date: 2016-04-13, Last modification date: 2024-01-10) |
Primary citation | Ursu, A.,Illich, D.J.,Takemoto, Y.,Porfetye, A.T.,Zhang, M.,Brockmeyer, A.,Janning, P.,Watanabe, N.,Osada, H.,Vetter, I.R.,Ziegler, S.,Scholer, H.R.,Waldmann, H. Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chem Biol, 23:494-507, 2016 Cited by PubMed: 27049670DOI: 10.1016/j.chembiol.2016.02.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report