5IGV

Macrolide 2'-phosphotransferase type II - complex with GDP and azithromycin

Summary for 5IGV

Entry DOI	10.2210/pdb5igv/pdb
Related	5IGU 5IGW 5IGY 5IGZ 5IH0 5IH1
Descriptor	Macrolide 2'-phosphotransferase II, MAGNESIUM ION, CALCIUM ION, ... (6 entities in total)
Functional Keywords	macrolide phosphotransferase, kinase, transferase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	35783.78
Authors	Berghuis, A.M.,Fong, D.H. (deposition date: 2016-02-28, release date: 2017-04-26, Last modification date: 2023-09-27)
Primary citation	Fong, D.H.,Burk, D.L.,Blanchet, J.,Yan, A.Y.,Berghuis, A.M. Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance. Structure, 25:750-761.e5, 2017 Cited by PubMed: 28416110 DOI: 10.1016/j.str.2017.03.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation