5IGS
Macrolide 2'-phosphotransferase type I - complex with guanosine and oleandomycin
Summary for 5IGS
Entry DOI | 10.2210/pdb5igs/pdb |
Related | 5IGH 5IGI 5IGJ 5IGP 5IGR 5IGT |
Descriptor | Macrolide 2'-phosphotransferase, ISOPROPYL ALCOHOL, (3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-6-HYDROXY-5,7,8,11,13,15-HEXAMETHYL-4,10-DIOXO-14-{[3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSYL]OXY}-1,9-DIOXASPIRO[2.13]HEXADEC-12-YL 2,6-DIDEOXY-3-O-METHYL-ALPHA-L-ARABINO-HEXOPYRANOSIDE, ... (5 entities in total) |
Functional Keywords | macrolide phosphotransferase, kinase, transferase-antibiotic complex, transferase/antibiotic |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 34298.02 |
Authors | Berghuis, A.M.,Fong, D.H. (deposition date: 2016-02-28, release date: 2017-04-26, Last modification date: 2023-09-27) |
Primary citation | Fong, D.H.,Burk, D.L.,Blanchet, J.,Yan, A.Y.,Berghuis, A.M. Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance. Structure, 25:750-761.e5, 2017 Cited by PubMed: 28416110DOI: 10.1016/j.str.2017.03.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.38 Å) |
Structure validation
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