5IGQ

WD40 domain of Human E3 Ubiquitin Ligase COP1 (RFWD2) bound to peptide from Trib1

Summary for 5IGQ

• Entry DOI: 10.2210/pdb5igq/pdb
• Descriptor: E3 ubiquitin-protein ligase RFWD2, Tribbles homolog 1 (3 entities in total)
• Functional Keywords: wd40 domain e3 ligase, tribbles, hydrolase-peptide complex, hydrolase/peptide
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus speckle: Q8NHY2
• Total number of polymer chains: 12
• Total formula weight: 245669.63

Authors

Uljon, S.,Blacklow, S.C. (deposition date: 2016-02-28, release date: 2016-04-20, Last modification date: 2023-09-27)

• Primary citation: Uljon, S.,Xu, X.,Durzynska, I.,Stein, S.,Adelmant, G.,Marto, J.A.,Pear, W.S.,Blacklow, S.C.; Structural Basis for Substrate Selectivity of the E3 Ligase COP1.; Structure, 24:687-696, 2016; PubMed: 27041596; DOI: 10.1016/j.str.2016.03.002

Experimental method

X-RAY DIFFRACTION (3.9 Å)