5IFO

X-ray structure of HSA-Myr-KP1019

Summary for 5IFO

Entry DOI	10.2210/pdb5ifo/pdb
Descriptor	Serum albumin, RUTHENIUM ION, MYRISTIC ACID, ... (4 entities in total)
Functional Keywords	complex, anticancer drug, serum protein, transport protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	68143.58
Authors	Bijelic, A.,Theiner, S.,Keppler, B.K.,Rompel, A. (deposition date: 2016-02-26, release date: 2016-06-01, Last modification date: 2024-01-10)
Primary citation	Bijelic, A.,Theiner, S.,Keppler, B.K.,Rompel, A. X-ray Structure Analysis of Indazolium trans-[Tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019) Bound to Human Serum Albumin Reveals Two Ruthenium Binding Sites and Provides Insights into the Drug Binding Mechanism. J.Med.Chem., 59:5894-5903, 2016 Cited by PubMed: 27196130 DOI: 10.1021/acs.jmedchem.6b00600 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation