5IFH
Crystal structure of the BCR Fab fragment from subset #2 case P11475
Summary for 5IFH
Entry DOI | 10.2210/pdb5ifh/pdb |
Descriptor | Heavy chain of the Fab fragment from BCR derived from the P11475 CLL clone, Light chain of the Fab fragment from BCR derived from the P11475 CLL clone (3 entities in total) |
Functional Keywords | immunoglobulin fold, b cell receptor, chronic lymphocytic leukemia, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 46976.19 |
Authors | Minici, C.,Degano, M. (deposition date: 2016-02-26, release date: 2017-03-08, Last modification date: 2024-01-10) |
Primary citation | Minici, C.,Gounari, M.,Ubelhart, R.,Scarfo, L.,Duhren-von Minden, M.,Schneider, D.,Tasdogan, A.,Alkhatib, A.,Agathangelidis, A.,Ntoufa, S.,Chiorazzi, N.,Jumaa, H.,Stamatopoulos, K.,Ghia, P.,Degano, M. Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia. Nat Commun, 8:15746-15746, 2017 Cited by PubMed: 28598442DOI: 10.1038/ncomms15746 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.293 Å) |
Structure validation
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