5IFE
Crystal structure of the human SF3b core complex
Summary for 5IFE
Entry DOI | 10.2210/pdb5ife/pdb |
Descriptor | Splicing factor 3B subunit 5, Splicing factor 3B subunit 1, PHD finger-like domain-containing protein 5A, ... (6 entities in total) |
Functional Keywords | pre-mrna splicing, u2 snrnp, essential splicing factor, splicing |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 307509.16 |
Authors | Cretu, C.,Dybkov, O.,De Laurentiis, E.,Will, C.L.,Luhrmann, R.,Pena, V. (deposition date: 2016-02-25, release date: 2016-10-26, Last modification date: 2024-05-08) |
Primary citation | Cretu, C.,Schmitzova, J.,Ponce-Salvatierra, A.,Dybkov, O.,De Laurentiis, E.I.,Sharma, K.,Will, C.L.,Urlaub, H.,Luhrmann, R.,Pena, V. Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations. Mol.Cell, 64:307-319, 2016 Cited by PubMed: 27720643DOI: 10.1016/j.molcel.2016.08.036 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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