5IFE

Crystal structure of the human SF3b core complex

Summary for 5IFE

Entry DOI	10.2210/pdb5ife/pdb
Descriptor	Splicing factor 3B subunit 5, Splicing factor 3B subunit 1, PHD finger-like domain-containing protein 5A, ... (6 entities in total)
Functional Keywords	pre-mrna splicing, u2 snrnp, essential splicing factor, splicing
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	307509.16
Authors	Cretu, C.,Dybkov, O.,De Laurentiis, E.,Will, C.L.,Luhrmann, R.,Pena, V. (deposition date: 2016-02-25, release date: 2016-10-26, Last modification date: 2024-05-08)
Primary citation	Cretu, C.,Schmitzova, J.,Ponce-Salvatierra, A.,Dybkov, O.,De Laurentiis, E.I.,Sharma, K.,Will, C.L.,Urlaub, H.,Luhrmann, R.,Pena, V. Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations. Mol.Cell, 64:307-319, 2016 Cited by PubMed: 27720643 DOI: 10.1016/j.molcel.2016.08.036 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation