5IEO
Structure of CDL2.3a, a computationally designed Vitamin-D3 binder
Summary for 5IEO
Entry DOI | 10.2210/pdb5ieo/pdb |
Related | 5IEN 5IEP 5IER 5IF6 |
Descriptor | CDL2.3a, 1,2-ETHANEDIOL, 3-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANOL, ... (4 entities in total) |
Functional Keywords | rossetta, ligand binder, computational, structural genomics, de novo protein |
Biological source | synthetic construct |
Total number of polymer chains | 1 |
Total formula weight | 15956.16 |
Authors | Stoddard, B.L.,Doyle, L.A. (deposition date: 2016-02-25, release date: 2017-03-01, Last modification date: 2023-09-27) |
Primary citation | Day, A.L.,Greisen, P.,Doyle, L.,Schena, A.,Stella, N.,Johnsson, K.,Baker, D.,Stoddard, B. Unintended specificity of an engineered ligand-binding protein facilitated by unpredicted plasticity of the protein fold. Protein Eng.Des.Sel., 31:375-387, 2018 Cited by PubMed: 30566669DOI: 10.1093/protein/gzy031 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.851 Å) |
Structure validation
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