5IC6
Crystal structure of caspase-7 DEVE peptide complex
Summary for 5IC6
Entry DOI | 10.2210/pdb5ic6/pdb |
Related | 5IC4 |
Descriptor | Caspase-7 subunit p20, Caspase-7 subunit p11, DEVE peptide (3 entities in total) |
Functional Keywords | apoptosis, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm: P55210 P55210 |
Total number of polymer chains | 6 |
Total formula weight | 71802.98 |
Authors | Seaman, J.E.,Julien, O.,Lee, P.S.,Rettenmaier, T.J.,Thomsen, N.D.,Wells, J.A. (deposition date: 2016-02-22, release date: 2016-07-20, Last modification date: 2023-11-15) |
Primary citation | Seaman, J.E.,Julien, O.,Lee, P.S.,Rettenmaier, T.J.,Thomsen, N.D.,Wells, J.A. Cacidases: caspases can cleave after aspartate, glutamate and phosphoserine residues. Cell Death Differ., 23:1717-1726, 2016 Cited by PubMed: 27367566DOI: 10.1038/cdd.2016.62 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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