5IAJ

Caspase 3 V266L

Summary for 5IAJ

Entry DOI	10.2210/pdb5iaj/pdb
Related PRD ID	PRD_000238
Descriptor	Caspase-3, ACE-ASP-GLU-VAL-ASK, SODIUM ION, ... (4 entities in total)
Functional Keywords	allostery, saturation mutagenesis, conformational selection, native ensemble, protein solvation, protein structure, protein dynamics, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (Human) More
Cellular location	Cytoplasm: P42574
Total number of polymer chains	2
Total formula weight	32337.06
Authors	Maciag, J.J.,Mackenzie, S.H.,Tucker, M.B.,Schipper, J.L.,Swartz, P.D.,Clark, A.C. (deposition date: 2016-02-21, release date: 2016-10-26)
Primary citation	Maciag, J.J.,Mackenzie, S.H.,Tucker, M.B.,Schipper, J.L.,Swartz, P.,Clark, A.C. Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection. Proc.Natl.Acad.Sci.USA, 113:E6080-E6088, 2016 Cited by PubMed: 27681633 DOI: 10.1073/pnas.1603549113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.58 Å)

Structure validation