5I8R

aSMase with zinc

5I8R の概要

• エントリーDOI: 10.2210/pdb5i8r/pdb
• 関連するPDBエントリー: 5I81 5I85
• 分子名称: Sphingomyelin phosphodiesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: acid sphingomyelinase, olipudase alfa, zinc, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 201859.98

構造登録者

Zhou, Y.F.,Wei, R.R. (登録日: 2016-02-19, 公開日: 2016-09-07, 最終更新日: 2023-09-27)

• 主引用文献: Zhou, Y.F.,Metcalf, M.C.,Garman, S.C.,Edmunds, T.,Qiu, H.,Wei, R.R.; Human acid sphingomyelinase structures provide insight to molecular basis of Niemann-Pick disease.; Nat Commun, 7:13082-13082, 2016; PubMed: 27725636; DOI: 10.1038/ncomms13082

実験手法

X-RAY DIFFRACTION (3.646 Å)