5I6C

The structure of the eukaryotic purine/H+ symporter, UapA, in complex with Xanthine

Summary for 5I6C

Entry DOI	10.2210/pdb5i6c/pdb
Descriptor	Uric acid-xanthine permease, XANTHINE, DODECYL-BETA-D-MALTOSIDE (3 entities in total)
Functional Keywords	membrane protein eukaryotic uric acid/xanthine h+ symporter, transport protein
Biological source	Aspergillus nidulans FGSC A4
Cellular location	Cell membrane ; Multi-pass membrane protein : Q07307
Total number of polymer chains	2
Total formula weight	124755.71
Authors	Alguel, Y.,Amillis, S.,Leung, J.,Lambrinidis, G.,Capaldi, S.,Scull, N.J.,Craven, G.,Iwata, S.,Armstrong, A.,Mikros, E.,Diallinas, G.,Cameron, A.D.,Byrne, B. (deposition date: 2016-02-16, release date: 2016-04-27, Last modification date: 2017-08-30)
Primary citation	Alguel, Y.,Amillis, S.,Leung, J.,Lambrinidis, G.,Capaldi, S.,Scull, N.J.,Craven, G.,Iwata, S.,Armstrong, A.,Mikros, E.,Diallinas, G.,Cameron, A.D.,Byrne, B. Structure of eukaryotic purine/H(+) symporter UapA suggests a role for homodimerization in transport activity. Nat Commun, 7:11336-11336, 2016 Cited by PubMed: 27088252 DOI: 10.1038/ncomms11336 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.7 Å)

Structure validation