5I6C

The structure of the eukaryotic purine/H+ symporter, UapA, in complex with Xanthine

5I6C の概要

• エントリーDOI: 10.2210/pdb5i6c/pdb
• 分子名称: Uric acid-xanthine permease, XANTHINE, DODECYL-BETA-D-MALTOSIDE (3 entities in total)
• 機能のキーワード: membrane protein eukaryotic uric acid/xanthine h+ symporter, transport protein
• 由来する生物種: Aspergillus nidulans FGSC A4
• 細胞内の位置: Cell membrane ; Multi-pass membrane protein : Q07307
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 124755.71

構造登録者

Alguel, Y.,Amillis, S.,Leung, J.,Lambrinidis, G.,Capaldi, S.,Scull, N.J.,Craven, G.,Iwata, S.,Armstrong, A.,Mikros, E.,Diallinas, G.,Cameron, A.D.,Byrne, B. (登録日: 2016-02-16, 公開日: 2016-04-27, 最終更新日: 2017-08-30)

• 主引用文献: Alguel, Y.,Amillis, S.,Leung, J.,Lambrinidis, G.,Capaldi, S.,Scull, N.J.,Craven, G.,Iwata, S.,Armstrong, A.,Mikros, E.,Diallinas, G.,Cameron, A.D.,Byrne, B.; Structure of eukaryotic purine/H(+) symporter UapA suggests a role for homodimerization in transport activity.; Nat Commun, 7:11336-11336, 2016; PubMed: 27088252; DOI: 10.1038/ncomms11336

実験手法

X-RAY DIFFRACTION (3.7 Å)