5I59
Glutamate- and glycine-bound GluN1/GluN2A agonist binding domains with MPX 007
Summary for 5I59
Entry DOI | 10.2210/pdb5i59/pdb |
Related | 5I56 5I57 5I58 |
Descriptor | Glutamate receptor ionotropic, NMDA 1,Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2A,Glutamate receptor ionotropic, NMDA 2A, GLYCINE, ... (6 entities in total) |
Functional Keywords | nmda receptor, antagonist, transport protein, receptor |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 2 |
Total formula weight | 65550.78 |
Authors | Mou, T.-C.,Sprang, S.R.,Hansen, K.B. (deposition date: 2016-02-14, release date: 2016-09-21, Last modification date: 2023-09-27) |
Primary citation | Yi, F.,Mou, T.C.,Dorsett, K.N.,Volkmann, R.A.,Menniti, F.S.,Sprang, S.R.,Hansen, K.B. Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors. Neuron, 91:1316-1329, 2016 Cited by PubMed: 27618671DOI: 10.1016/j.neuron.2016.08.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
Download full validation report