5I4R

Contact-dependent inhibition system from Escherichia coli NC101 - ternary CdiA/CdiI/EF-Tu complex (trypsin-modified)

5I4R の概要

• エントリーDOI: 10.2210/pdb5i4r/pdb
• 分子名称: Contact-dependent inhibitor A, Elongation factor Tu, Contact-dependent inhibitor I, ... (5 entities in total)
• 機能のキーワード: toxin, antitoxin, elongation factor, structural genomics, psi-biology, midwest center for structural genomics, mcsg, structure-function analysis of polymorphic cdi toxin-immunity protein complexes, uc4cdi, toxin-antitoxin complex, toxin/antitoxin
• 由来する生物種: Escherichia coli NC101; 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 133836.14

構造登録者

Michalska, K.,Stols, L.,Eschenfeldt, W.,Hayes, C.S.,Goulding, C.W.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG),Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) (登録日: 2016-02-12, 公開日: 2017-06-28, 最終更新日: 2023-11-15)

• 主引用文献: Michalska, K.,Gucinski, G.C.,Garza-Sanchez, F.,Johnson, P.M.,Stols, L.M.,Eschenfeldt, W.H.,Babnigg, G.,Low, D.A.,Goulding, C.W.,Joachimiak, A.,Hayes, C.S.; Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs.; Nucleic Acids Res., 45:10306-10320, 2017; PubMed: 28973472; DOI: 10.1093/nar/gkx700

実験手法

X-RAY DIFFRACTION (3.3 Å)