5I13

Endonuclease inhibitor 2 bound to influenza strain H1N1 polymerase acidic subunit N-terminal region at pH 7.0

Replaces:  5FDE

Summary for 5I13

• Entry DOI: 10.2210/pdb5i13/pdb
• Related: 4ZI0
• Descriptor: Polymerase acidic protein, MANGANESE (II) ION, SULFATE ION, ... (5 entities in total)
• Functional Keywords: hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)
• Total number of polymer chains: 1
• Total formula weight: 23063.81

Authors

Fudo, S.,Yamamoto, N.,Nukaga, M.,Odagiri, T.,Tashiro, M.,Hoshino, T. (deposition date: 2016-02-05, release date: 2016-02-17, Last modification date: 2023-11-08)

• Primary citation: Fudo, S.,Yamamoto, N.,Nukaga, M.,Odagiri, T.,Tashiro, M.,Hoshino, T.; Two Distinctive Binding Modes of Endonuclease Inhibitors to the N-Terminal Region of Influenza Virus Polymerase Acidic Subunit; Biochemistry, 55:2646-2660, 2016; PubMed: 27088785; DOI: 10.1021/acs.biochem.5b01087

Experimental method

X-RAY DIFFRACTION (2.151 Å)