5HZK

Crystal structure of photoinhibitable Intersectin1 containing wildtype LOV2 domain in complex with Cdc42

5HZK の概要

• エントリーDOI: 10.2210/pdb5hzk/pdb
• 分子名称: Cell division control protein 42 homolog, Intersectin-1,NPH1-1,Intersectin-1, GUANOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: signaling protein, photoswitch, chimera, complex
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cell membrane ; Lipid-anchor ; Cytoplasmic side : P60953; Endomembrane system : Q15811
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 160527.68

構造登録者

Tarnawski, M.,Dagliyan, O.,Chu, P.H.,Shirvanyants, D.,Dokholyan, N.V.,Hahn, K.M.,Schlichting, I. (登録日: 2016-02-02, 公開日: 2016-12-21, 最終更新日: 2024-01-10)

• 主引用文献: Dagliyan, O.,Tarnawski, M.,Chu, P.H.,Shirvanyants, D.,Schlichting, I.,Dokholyan, N.V.,Hahn, K.M.; Engineering extrinsic disorder to control protein activity in living cells.; Science, 354:1441-1444, 2016; PubMed: 27980211; DOI: 10.1126/science.aah3404

実験手法

X-RAY DIFFRACTION (3.3 Å)