5HYL

Crystal structure of DR2231_E47A mutant in complex with dUMPNPP and magnesium

Summary for 5HYL

• Entry DOI: 10.2210/pdb5hyl/pdb
• Descriptor: DR2231, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: alpha helix, hydrolase
• Biological source: Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
• Total number of polymer chains: 4
• Total formula weight: 66436.64

Authors

Mota, C.S.,Goncalves, A.M.D.,de Sanctis, D. (deposition date: 2016-02-01, release date: 2016-10-26, Last modification date: 2024-01-10)

• Primary citation: Mota, C.S.,Goncalves, A.M.,de Sanctis, D.; Deinococcus radiodurans DR2231 is a two-metal-ion mechanism hydrolase with exclusive activity on dUTP.; FEBS J., 283:4274-4290, 2016; PubMed: 27739259; DOI: 10.1111/febs.13923

Experimental method

X-RAY DIFFRACTION (1.8 Å)