5HWU
Crystal Structure of DR2231_E46A mutant in complex with dUMPNPP and Manganese
Summary for 5HWU
Entry DOI | 10.2210/pdb5hwu/pdb |
Descriptor | DR2231, MANGANESE (II) ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | alpha helix, hydrolase |
Biological source | Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422) |
Total number of polymer chains | 2 |
Total formula weight | 30673.70 |
Authors | Mota, C.S.,Goncalves, A.M.D.,de Sanctis, D. (deposition date: 2016-01-29, release date: 2016-10-26, Last modification date: 2024-01-10) |
Primary citation | Mota, C.S.,Goncalves, A.M.,de Sanctis, D. Deinococcus radiodurans DR2231 is a two-metal-ion mechanism hydrolase with exclusive activity on dUTP. FEBS J., 283:4274-4290, 2016 Cited by PubMed: 27739259DOI: 10.1111/febs.13923 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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