5HWU

Crystal Structure of DR2231_E46A mutant in complex with dUMPNPP and Manganese

Summary for 5HWU

Entry DOI	10.2210/pdb5hwu/pdb
Descriptor	DR2231, MANGANESE (II) ION, GLYCEROL, ... (5 entities in total)
Functional Keywords	alpha helix, hydrolase
Biological source	Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Total number of polymer chains	2
Total formula weight	30673.70
Authors	Mota, C.S.,Goncalves, A.M.D.,de Sanctis, D. (deposition date: 2016-01-29, release date: 2016-10-26, Last modification date: 2024-01-10)
Primary citation	Mota, C.S.,Goncalves, A.M.,de Sanctis, D. Deinococcus radiodurans DR2231 is a two-metal-ion mechanism hydrolase with exclusive activity on dUTP. FEBS J., 283:4274-4290, 2016 Cited by PubMed: 27739259 DOI: 10.1111/febs.13923 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation