5HVW
Monomeric IgG4 Fc
5HVW の概要
エントリーDOI | 10.2210/pdb5hvw/pdb |
分子名称 | Ig gamma-4 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (5 entities in total) |
機能のキーワード | biotechnology, antibody engineering, monomeric fc, monovalent targeting, fusion protein, immune system |
由来する生物種 | Homo sapiens (Human) |
細胞内の位置 | Secreted: P01861 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 25748.28 |
構造登録者 | |
主引用文献 | Shan, L.,Colazet, M.,Rosenthal, K.L.,Yu, X.Q.,Bee, J.S.,Ferguson, A.,Damschroder, M.M.,Wu, H.,Dall'Acqua, W.F.,Tsui, P.,Oganesyan, V. Generation and Characterization of an IgG4 Monomeric Fc Platform. Plos One, 11:e0160345-e0160345, 2016 Cited by PubMed: 27479095DOI: 10.1371/journal.pone.0160345 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.95 Å) |
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