5HRT

Crystal structure of mouse autotaxin in complex with a DNA aptamer

Summary for 5HRT

• Entry DOI: 10.2210/pdb5hrt/pdb
• Descriptor: Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, GLYCEROL, modified DNA (34-MER), ... (11 entities in total)
• Functional Keywords: phospholipase d, dna aptamer, hydrolase
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 2
• Total formula weight: 109700.63

Authors

Kato, K.,Nishimasu, H.,Morita, J.,Ishitani, R.,Nureki, O. (deposition date: 2016-01-24, release date: 2016-04-06, Last modification date: 2020-07-29)

• Primary citation: Kato, K.,Ikeda, H.,Miyakawa, S.,Futakawa, S.,Nonaka, Y.,Fujiwara, M.,Okudaira, S.,Kano, K.,Aoki, J.,Morita, J.,Ishitani, R.,Nishimasu, H.,Nakamura, Y.,Nureki, O.; Structural basis for specific inhibition of Autotaxin by a DNA aptamer; Nat.Struct.Mol.Biol., 23:395-401, 2016; PubMed: 27043297; DOI: 10.1038/nsmb.3200

Experimental method

X-RAY DIFFRACTION (1.997 Å)