5HNS

Structure of glycosylated NPC1 luminal domain C

5HNS の概要

• エントリーDOI: 10.2210/pdb5hns/pdb
• 分子名称: Niemann-Pick C1 protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: niemann-pick disease type c, npc1, npc2, cholesterol transport, ebola virus receptor, ebola virus susceptibility, protein binding
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 60725.66

構造登録者

Zhao, Y.,Ren, J.,Harlos, K.,Stuart, D.I. (登録日: 2016-01-18, 公開日: 2016-02-10, 最終更新日: 2020-07-29)

• 主引用文献: Zhao, Y.,Ren, J.,Harlos, K.,Stuart, D.I.; Structure of glycosylated NPC1 luminal domain C reveals insights into NPC2 and Ebola virus interactions.; Febs Lett., 590:605-612, 2016; PubMed: 26846330; DOI: 10.1002/1873-3468.12089

実験手法

X-RAY DIFFRACTION (2.45 Å)