5HNM

Crystal structure of vancomycin resistance D,D-pentapeptidase VanY E175A mutant from VanB-type resistance cassette in complex with Zn(II)

Summary for 5HNM

• Entry DOI: 10.2210/pdb5hnm/pdb
• Descriptor: D-alanyl-D-alanine carboxypeptidase, ZINC ION, SULFATE ION, ... (4 entities in total)
• Functional Keywords: center for structural genomics of infectious diseases, csgid, national institute of allergy and infectious diseases, niaid, alpha+beta protein, metallopeptidase, hedgehog/dd-peptidase fold, merops m15b subfamily, zn2+-dependent, vancomycin resistance, antibiotic resistance, hydrolase
• Biological source: Enterococcus faecalis (strain ATCC 700802 / V583)
• Cellular location: Cell membrane ; Single-pass membrane protein : Q47746
• Total number of polymer chains: 6
• Total formula weight: 135090.40

Authors

Stogios, P.J.,Chun, J.,Wawrzak, Z.,Evdokimova, E.,Di Leo, R.,Yim, V.,Courvalin, P.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2016-01-18, release date: 2016-02-10, Last modification date: 2023-09-27)

• Primary citation: Stogios, P.J.; To be published; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)