5HNM

Crystal structure of vancomycin resistance D,D-pentapeptidase VanY E175A mutant from VanB-type resistance cassette in complex with Zn(II)

5HNM の概要

• エントリーDOI: 10.2210/pdb5hnm/pdb
• 分子名称: D-alanyl-D-alanine carboxypeptidase, ZINC ION, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: center for structural genomics of infectious diseases, csgid, national institute of allergy and infectious diseases, niaid, alpha+beta protein, metallopeptidase, hedgehog/dd-peptidase fold, merops m15b subfamily, zn2+-dependent, vancomycin resistance, antibiotic resistance, hydrolase
• 由来する生物種: Enterococcus faecalis (strain ATCC 700802 / V583)
• 細胞内の位置: Cell membrane ; Single-pass membrane protein : Q47746
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 135090.40

構造登録者

Stogios, P.J.,Chun, J.,Wawrzak, Z.,Evdokimova, E.,Di Leo, R.,Yim, V.,Courvalin, P.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2016-01-18, 公開日: 2016-02-10, 最終更新日: 2023-09-27)

• 主引用文献: Stogios, P.J.; To be published; To Be Published,

実験手法

X-RAY DIFFRACTION (2.3 Å)