5HLA

E. coli PBP1b in complex with acyl-cephalexin and moenomycin

Summary for 5HLA

Entry DOI	10.2210/pdb5hla/pdb
Related	5HL9 5HLB 5HLD
Descriptor	Penicillin-binding protein 1B, (2S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5-methyl-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, MOENOMYCIN, ... (4 entities in total)
Functional Keywords	penicillin-binding protein, inhibitor complex, transpeptidase, transglycosylase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Escherichia coli (strain K12)
Total number of polymer chains	1
Total formula weight	85210.32
Authors	King, D.T.,Strynadka, N.C.J. (deposition date: 2016-01-14, release date: 2016-12-14, Last modification date: 2023-09-27)
Primary citation	King, D.T.,Wasney, G.A.,Nosella, M.,Fong, A.,Strynadka, N.C. Escherichia coli Penicillin-Binding Protein 1B: Structural Insights into Inhibition. J. Biol. Chem., 2016 Cited by PubMed: 27899450 DOI: 10.1074/jbc.M116.718403 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.36 Å)

Structure validation