5HKY

Crystal structure of c-Cbl TKBD domain in complex with SPRY2 peptide (36-60, pY55) Refined to 1.8A Resolution (P6 form)

Summary for 5HKY

• Entry DOI: 10.2210/pdb5hky/pdb
• Related: 5HKW 5HKX 5HKZ 5HL0
• Descriptor: E3 ubiquitin-protein ligase CBL, Protein sprouty homolog 2, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: spry2, cbl, protein-protein interaction, anticancer target, ligase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 39026.57

Authors

Lovell, S.,Battaile, K.P.,Mehzabeen, N.,Zhang, N.,Cooper, A.,Gao, P.,Perez, R.P. (deposition date: 2016-01-14, release date: 2017-01-18, Last modification date: 2024-10-30)

• Primary citation: Zhang, N.,Ferris, D.,Lovell, S.,Smalter-Hall, A.,Battaile, K.P.,Anbanandam, A.,Gao, P.,Hanzlik, R.,Perez, R.P.; Crystal structure of c-Cbl TKBD domain in complex with SPRY2 peptide (36-60, pY55) Refined to 1.8A Resolution (P6 form); To be published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)