5HK1

Human sigma-1 receptor bound to PD144418

Summary for 5HK1

• Entry DOI: 10.2210/pdb5hk1/pdb
• Descriptor: Sigma non-opioid intracellular receptor 1, 3-(4-methylphenyl)-5-(1-propyl-3,6-dihydro-2H-pyridin-5-yl)-1,2-oxazole, SULFATE ION, ... (5 entities in total)
• Functional Keywords: sigma-1 receptor, transmembrane receptor, signal transduction, membrane protein
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus inner membrane: Q99720
• Total number of polymer chains: 3
• Total formula weight: 81031.44

Authors

Schmidt, H.R.,Zheng, S.,Gurpinar, E.,Koehl, A.,Manglik, A.,Kruse, A.C. (deposition date: 2016-01-13, release date: 2016-04-06, Last modification date: 2024-03-06)

• Primary citation: Schmidt, H.R.,Zheng, S.,Gurpinar, E.,Koehl, A.,Manglik, A.,Kruse, A.C.; Crystal structure of the human sigma 1 receptor.; Nature, 532:527-530, 2016; PubMed: 27042935; DOI: 10.1038/nature17391

Experimental method

X-RAY DIFFRACTION (2.5051 Å)