5HHV
Inhibiting complex IL-17A and IL-17RA interactions with a linear peptide
Summary for 5HHV
Entry DOI | 10.2210/pdb5hhv/pdb |
Related | 5HHX 5HI3 5HI4 5HI5 |
Descriptor | Interleukin-17A, CAT-2000 FAB heavy chain, IL-17A peptide inhibitor, ... (5 entities in total) |
Functional Keywords | il-17, inflammation, inhibitor, complex crystal structure, immune system-inhibitor complex, immune system/inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted: Q16552 |
Total number of polymer chains | 5 |
Total formula weight | 78381.25 |
Authors | |
Primary citation | Liu, S.,Desharnais, J.,Sahasrabudhe, P.V.,Jin, P.,Li, W.,Oates, B.D.,Shanker, S.,Banker, M.E.,Chrunyk, B.A.,Song, X.,Feng, X.,Griffor, M.,Jimenez, J.,Chen, G.,Tumelty, D.,Bhat, A.,Bradshaw, C.W.,Woodnutt, G.,Lappe, R.W.,Thorarensen, A.,Qiu, X.,Withka, J.M.,Wood, L.D. Inhibiting complex IL-17A and IL-17RA interactions with a linear peptide. Sci Rep, 6:26071-26071, 2016 Cited by PubMed: 27184415DOI: 10.1038/srep26071 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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