5HHH

Structure of human DNA polymerase beta Host-Guest complexed with the control G for N7-CBZ-platination

Summary for 5HHH

• Entry DOI: 10.2210/pdb5hhh/pdb
• Related: 5HHI
• Descriptor: DNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*AP*GP*GP*AP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*TP*CP*CP*TP*C)-3'), ... (6 entities in total)
• Functional Keywords: transferase, lyase-dna complex, lyase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 46823.70

Authors

Koag, M.-C.,Lee, S. (deposition date: 2016-01-11, release date: 2017-01-18, Last modification date: 2023-09-27)

• Primary citation: Cheun, Y.,Koag, M.C.,Naguib, Y.W.,Ouzon-Shubeita, H.,Cui, Z.,Pakotiprapha, D.,Lee, S.; Synthesis, structure, and biological evaluation of a platinum-carbazole conjugate.; Chem Biol Drug Des, 91:116-125, 2018; PubMed: 28649747; DOI: 10.1111/cbdd.13062

Experimental method

X-RAY DIFFRACTION (2.363 Å)